Chloroquine Resistance in Malaria: Accessibility of Drug
نویسندگان
چکیده
mouse erythrocytes accumulated more than half as much mefloquine as infected erythrocytes. The process of accumulation was not stimulated by providing glucose as a substrate, and it was not inhibited in infected erythrocytes by azide, iodoacetate, or incubation at 2°C. Although mefloquine was accumulated more effectively than chloroquine by uninfected erythrocytes and by erythrocytes infected with P. berghei CR, competition between chloroquine and mefloquine
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داروهای ضدمالاریا
One of the most important drug which use in malaria treatment is chloroguine, this drug has schizontocidal effect (except in the cases of plasmodium falciparum resistance to chloroquine). Primaquine had effect on exoerythrocytic stage of malaria parasite and use for radical cure of malaria. Quinine is a useful drug especially in cerebral malaria treatment. Today antibiotic. Mefloquine , su...
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